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KMID : 0882420150880060737
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Korean Journal of Medicine
2015 Volume.88 No. 6 p.737 ~ p.741
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A Case of Thyrotropin (TSH)-Secreting Pituitary Adenoma in a Patient with Ankylosing Spondylitis
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Park Ji-Hye
Lee Seong-Geun
Park Eun-Kyoung
Koo Dong-Wan
Kim Bo-Hyun
Kim In-Ju
Kim Geun-Tae
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Abstract
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A thyrotropin (TSH)-secreting pituitary adenoma is a rare cause of hyperthyroidism, with an incidence of one case per million. Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease of the axial skeleton. Extra-articular manifestations, such as anterior uveitis, may also be prominent features in AS but little is known about the association between AS and thyroid diseases including TSH-secreting pituitary adenomas. We present a case study of a 26-year-old male AS patient who was diagnosed with a TSH-secreting pituitary adenoma using a thyrotropin releasing hormone stimulation test, measurement of the TSH α-subunit, and magnetic resonance imaging, and subsequently treated with a transsphenoidal tumor resection.
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KEYWORD
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Pituitary neoplasms, Thyrotropin, Spondylitis, Ankylosing
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